Dr. Arthur Lander

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Publications

1. Lander, A.D., D.K. Fujii, D. Gospodarowicz and L.F. Reichardt, (1982).Characterization of a factor that promotes neurite outgrowth: evidence linking activity to a heparan sulfate proteoglycan. J. Cell Biol. 94, 574-585.

2. Lander, A.D., Tomaselli, K., Calof, A.L. and Reichardt, L.F., (1983). Studies on extracellular matrix components that promote neurite outgrowth. Cold Spring Harbor Symp. Quant. Biology XLVIII, 661-623.

3. Reichardt, L.F., W.D. Matthew, A.D. Lander, K. Tomaselli, R. Greenspan, and Greif, K., (1984). Applications of monoclonal antibodies to studies on neurite growth and synapse formation. In Neuroimmunology, P. Behan and F. Spreafico, Editors. Raven Press, New York.

4. Matthew, W.D., R.J. Greenspan, A.D. Lander, and L.F. Reichardt, (1985). Immunopurification and characterization of a neuronal heparan sulfate proteoglycan. J. Neurosci. 5, 1842-1850.

5. Lander, A.D., D.K. Fujii, and L.F. Reichardt, (1985). Purification of a factor that promotes neurite outgrowth: isolation of laminin and associated molecules. J. Cell Biol. 101, 898-913.

6. Lander, A.D., D.K. Fujii, and L.F. Reichardt, (1985). Laminin is associated with the “neurite outgrowth-promoting factors” found in conditioned media. Proc. Natl. Sci. USA 82, 2183-2187.

7. Lander, A.D. (1987). Molecules that make axons grow. Molecular Neurobiology, 1, 213-245.

8. Reichardt, L.F., J.L. Bixby, D.E. Hall, M.J. Ignatius, A.D. Lander, Neugebauer, K.M., Tomaselli, K.L. (1988). Glyoproteins that regulate axon growth. In: Molecular Neurobiology: Proceedings of the First NIMH Conference. S. Zalcman and R. Scheller, Eds. U.S. Gov’t Printing Office. pp. 110-127.

9. Lander, A.D. (1989). Understanding the molecules of neural cell contacts: emerging patterns of structure and function. Trends in Neurosciences, 12, 189-195.

10. Herndon, M.E. and A.D. Lander (1990). A diverse set of developmentally regulated proteoglycans is expressed in rat central nervous system. Neuron 4, 949-961.

11. Lander, A.D. (1990) Mechanisms by which molecules guide axons. Curr. Opinions Cell Biol., 2, 907-913.

12. Lee, M.K., and A.D. Lander (1991). Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: development of a sensitive electrophoretic approach. Proc. Natl. Acad. Sci., 88, 2768-2772.

13. Lim, W., R. Sauer, and A.D. Lander (1991). Analysis of DNA-protein interactions by affinity co-electrophoresis. Methods in Enzymol. 208,196-210.

14. Birgbauer, E., J.H. Dinsmore, A.D. Lander and F. Solomon (1991). Association of ezrin isoforms with the neuronal cytoskeleton. J. Neurosci. Res. 30, 232-241.

15. Calof, A.L. and A.D. Lander (1991). Relationship between neuronal migration and cell-substratum adhesion: Laminin and merosin promote olfactory neuron migration but are anti-adhesive. J. Cell Biol. 115, 779-794

16. Sanderson, R.D., T.B. Sneed, L.A. Maes, G.S. Sullivan and A.D. Lander (1991). Adhesion of B lymphoid (MPC-11) cells to type I collagen is mediated by the integral membrane proteoglycan, syndecan. J. Immunol. 148, 3902-3911.

17. Calof, A.L., A.D. Lander and D.M. Chikaraishi (1991). Regulation of neurogenesis and neuronal differentiation in primary and immortalized cells from mouse olfactory epithelium. In Regeneration of Vertebrate Sensory Receptor Cells. Wiley, Chichester (Ciba Foundation Symposium 160). pp. 249-276.

18. San Antonio, J.D., A.D. Lander, T.C. Wright, and M.J. Karnovsky (1992). Heparin inhibits the attachment and growth of Balb/c-3T3 fibroblasts on collagenous substrata. J. Cell. Physiol. 150, 8-16.

19. Hynes, R.O. and A.D. Lander, (1992) Contact and adhesive specificties in the associations, migrations and targetting of cells and axons. Cell 68, 303-322.

20. San Antonio, J.D., J. Slover, J. Lawler, M.J. Karnovsky and A.D. Lander (1993). Specificity in the interactions of extracellular matrix proteins with subpopulations of the glycosaminoglycan heparin. Biochemistry, 32, 4746-4755.

21. Lander, A.D. (1993). Proteoglycans. In: Guidebook to the Extracellular Matrix and Adhesion Proteins. T. Kreis and R. Vale, Eds. Oxford Univ. Press, pp. 12-16

22. Lander, A.D. and A.L. Calof (1993). Extracellular matrix in the developing nervous system. In: Molecular Genetics of Nervous System Tumors, A.J. Levine and H.H. Schmidek, Eds., Wiley-Liss, New York. pp. 341-355.

23. Lander, A.D. (1993). Proteoglycans in the nervous system. Curr. Opinions Neurobiol. 3, 716-723.

24. Stipp, C.S., E.D. Litwack and A.D. Lander (1994). Cerebrogylcan: An integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation. J. Cell Biol. 124, 149-160.

25. Litwack, E.D., C.S Stipp and A.D. Lander (1994). Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system. J. Neurosci. 14, 3713-3724.

26. Sanderson, R.D., J. Turnbull, J.T. Gallagher and A.D. Lander (1994). Structure of heparan sulfate regulates proteoglycan function and cell behavior. J. Biol. Chem. 269, 13100-13106.

27. Witt, D.P. and A.D. Lander (1994). Differential binding of chemokines to glycosaminoglycan subpopulations. Current Biology. 4, 394-400.

28. San Antonio, J.D., A.D. Lander, M.J. Karnovsky and H.S. Slayter (1994). Mapping the heparin binding sites on type I collagen monomers and fibrils. J. Cell Biol. 125, 1179-1188.

29. Calof, A.L., M.R. Campanero, J.J. O’Rear, P.D. Yurchenco and A.D. Lander (1994). Domain-specific activation of neuronal migration and neurite outgrowth-promoting activities of laminin. Neuron 13, 117-130.

30. San Antonio, J.D., M.J. Karnovsky, S. Gay, R.D. Sanderson and A.D. Lander (1994). Interactions of syndecan-1 and heparin with human collagens. Glycobiology 4, 327-332.

31. Calof, A.L., M.D. Adusumalli, M.K. DeHamer, J.L. Guevara, J.S. Mumm, S.J. Whitehead and A.D. Lander (1994). Generation, differentiation and maturation of olfactory receptor neurons in vitro. In: Olfaction and Taste XI. K. Kurihara, N. Suzuki and H. Ogawa, Eds., Springer Verlag, Tokyo. pp. 36-40.

32. Emerling, D. and A.D. Lander (1994). Laminar-specific behaviors of thalamic neurons on cultured slices of embryonic cerebral cortex. Development 120, 2811-2822 .

33. Lander, A.D. (1994). Targeting the glycosaminoglycan-binding sites of proteins. Chemistry and Biology 1, 73-78.

34. Kindt, R.M. and A.D. Lander (1995). Pertussis toxin inhibits growth cone guidance by a mechanism independent of direct G-protein inactivation. Neuron 15, 79-88.

35. Magendantz, M., M.D. Henry, A.D. Lander and F. Solomon (1995). Inter-domain interactions of radixin in vitro. J. Biol. Chem. 270, 25324-25327.

36. Williamson, T.G., S.S. Mok, A. Henry, R. Cappai, A.D. Lander, V. Nurcombe, K. Beyreuther, C.L. Masters and D.H. Small (1996) Glypican binds to the amyloid precursor protein of Alzheimer’s disease (APP) and inhibits APP-induced neurite outgrowth. J. Biol. Chem. 271 , 31215-31221.

37. Emerling, D.E. and A.D. Lander (1996) Inhibitors and promoters of thalamic neuron adhesion and outgrowth in embryonic neocortex: functional association with chondroitin sulfate. Neuron 17, 1089-1100.

38. Lander, A.D., C.S. Stipp and J.K. Ivins (1996) The Glypican Family of Heparan Sulfate Proteoglycans: Major Cell-Surface Proteoglycans of the Developing Nervous System. Perspectives Devel. Neurobiol. 3, 347-358.

39. Herndon, M.E. and A.D. Lander (1996) Analysis of protein-glycosaminoglycan interactions by affinity co-electrophoresis. In: A Laboratory Guide to Glycoconjugate Analysis. P. Jackson and J.T. Gallagher, Eds., Birkhauser Verlag, Basel. BioMethods, 9, 377-396.

40. Ivins, J.K., E.D. Litwack, A. Kumbasar, C.S. Stipp and A.D. Lander (1996) Cerebroglycan is a neuronal cell surface heparan sulfate proteoglycan expressed on developing axons and growth cones. Developmental Biology 184, 330-322.

41. Saunders, S., S. Paine-Saunders, and A.D. Lander (1997) Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb and brain. Developmental Biology, 190, 78-93.

42. Watson, D.J., A.D. Lander and D.J. Selkoe (1997) Heparin-binding properties of the amyloidogenic peptides A-beta and amylin: dependence on aggregation state and inhibition by Congo red. J. Biol. Chem. 272, 31617-31624.

43. Litwack, E.D., J.K. Ivins, A. Kumbasar, S.E. Paine-Saunders, C.S. Stipp and A.D. Lander (1998) Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent. Developmental Dynamics, 211, 72-87.

44. Hoffman-Kim, D., A.D. Lander and S. Jhaveri (1998) Regional differences in immunostaining for chondroitin sulfate in the developing tectum reflect differential GAG biosynthesis. J. Neurosci., 18, 5881-5890.

45. Liu, W., E.D. Litwack, A.D. Lander, M.H. Stanley, J.K. Langford and R.D. Sanderson (1998) Heparan sulfate proteoglycans as adhesive and anti-invasive molecules: syndecans and glypican have distinct functions. J. Biol. Chem., 35, 22825-22832.

46. Ivins, J.K., H Colognato, J. A. Kreidberg, P. D. Yurchenco and A. D. Lander (1998) Neuronal receptors mediating responses to antibody-activated laminin-1. J. Neurosci. 18, 9703-9715.

47. Kleef, J, T. Ishiwata, A. Kumbasar, H. Friess, M.W. Büchler, A.D. Lander and M. Korc (1998) The cell surface heparan sulfate proteoglycan glypican-1 is an essential regulator of growth factor action in pancreatic carcinoma cells, and is overexpressed in human pancreatic cancer. J. Clin. Invest. 102, 1662-1673.

48. Lander, A.D. (1998) Proteoglycans: Master regulators of molecular encounter? Matrix Biology, 17, 465-472.

49. Lander, A.D. (1999). Proteoglycans. In: Guidebook to the Extracellular Matrix and Adhesion Proteins. 2nd Edition. T. Kreis and R. Vale, Eds. Oxford Univ. Press, pp. 351-356.

50. Herndon, M.E., C.S. Stipp and A.D. Lander (1999) Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: assessment of selectivity, heterogeneity, and the participation of core proteins in binding. Glycobiology 9, 143-155.

51. Lander, A.D. (1999) Seeking the functions of cell surface heparan sulphate proteoglycans. In Cell Surface Proteoglycans in Signalling and Development (Human Frontiers Science Program Workshop VI), A.D. Lander, H. Nakato, S. Selleck, J. Turnbull, and C. Coath, Eds. HFSP, Strasbourg, pp. 73-87.

52. Kleef, J., S. Wildi, A. Kumbasar, H. Friess, A.D. Lander and M. Korc (1999) Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells. Pancreas, 19, 281-288.

53. Wildi, S., J. Kleeff, H. Maruyama, C.A. Maurer, H. Friess, M.W. Büchler, A.D. Lander and M. Korc (1999) Characterization of cytokeratin 20 expression in pancreatic and colorectal cancer. Clinical Cancer Res. 5, 2840-2847.

54. Lander, A.D. and S. Selleck (2000) The elusive functions of proteoglycans: In vivo veritas. J. Cell Biol. 148, 227-232.

55. Ivins J.K., P.D. Yurchenco, and A.D. Lander (2000) Regulation of neurite outgrowth by integrin activation. J. Neurosci. 20, 6551-6560.

56. Emerling D.E., and A.D. Lander (2000) Using organotypic tissue slices as substrata for the culture of dissociated cells. Methods Mol Biol 139, 245-256.

57. Zhu, Z.-w., H. Friess, L. Wang, M. Abou-Shady, A. Zimmermann, A.D. Lander, M. Korc, J. Kleeff and M. BŸchler (2001) Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders. Gut, 48, 558-564.

58. Chen, R.L. and A.D. Lander (2001) Mechanisms underlying preferential assembly of heparan sulfate on glypican-1. J. Biol. Chem. 267, 7507-7517.

59. Karumanchi SA, V Jha , R Ramchandran , A Karihaloo , L Tsiokas , B Chan, M Dhanabal, J-i Hanai, G Venkataraman, Z Shriver, N Keiser, R Kalluri, H Zeng, D Mukhopadhyay, R L Chen, AD Lander, K Hagihara, Y Yamaguchi, R Sasisekharan, L Cantley, and V P. Sukhatme (2001) Cell Surface Glypicans Are Low-Affinity Endostatin Receptors. Molecular Cell 7, 811-822.

60. San Antonio, J. and A.D. Lander (2001) Affinity coelectrophoresis of proteoglycan-protein complexes. In: Methods in Molecular Biology vol 171: Proteoglycan Protocols, R.V. Iozzo, Ed., Humana Press, Totowa NJ, pp. 401-414.

61. Matsuda, K., H. Maruyama, F. Guo, J. Kleeff, J. Itakura, Y. Matsumoto, A.D. Lander and M. Korc (2001) Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells. Cancer Research, 61,.5562-5569.

62. Lander, A.D., Q. Nie and F.Y.-M. Wan (2002) Do morphogen gradients arise by diffusion? Developmental Cell 2, 785-796.

63. Tsai, E.S., S. J. Haraldson, J. Baratta, A.D. Lander, J. Yu and R. T. Robertson (2002) Basal forebrain cholinergic cell attachment and neurite outgrowth on organotypic slice cultures of hippocampal formation, Neuroscience 115, 815-827.

64. Murray, R.C., D. Navi, J. Fesenko, A.D. Lander, and A.L. Calof (2003) Widespread defects in the primary olfactory pathway caused by loss of MASH1 function. J. Neurosci. 23, 1769-1780.

65. Kao, J., Nie, Q., Teng, A., Wan, F., Lander, A. and Marsh, J.L. (2003) Can morphogen activity be enhanced by its inhibitors? Proc of 2nd MIT Conference on Computational Fluid and Solid Mechanics, 2, 1729-1733.

66. Krantz, I D, J. McCallum, C. DeScipio, M. Kaur, L. A. Gillis, D. Yaeger, L. Jukofsky, N. Wasserman, A. Bottani, C.A. Morris, M.J.M. Nowaczyk, H. Toriello, M.J. Bamshad, J.C. Carey, E. Rappaport, S. Kawauchi, A.D. Lander, A.L. Calof , H-h Li, M. Devot, L.G. Jackson (2004) Cornelia de Lange Syndrome is caused by Mutations in NIPBL, the human homolog of the Drosophila Nipped-B gene. Nature Genetics, 36, 631-635.

67. Lander, A.D. (2004) A calculus of purpose. PloS Biology 2, 712-714.

68. Lander, A.D., Q. Nie, and F.Y.M. Wan (2005) Aggregation of a distributed source in morphogen gradient formation. Studies in Applied Mathematics, 114, 343-374.

69. Lander, A.D., Q. Nie, and F.Y.M. Wan (2005). Spatially distributed morphogen synthesis and morphogen gradient formation. Math Biosci & Eng. 2, 239-262.

70. Mizutani C.M., Q. Nie, F.Y.M. Wan, Y.-T. Zhang, P. Vilmos, R. Sousa-Neves, E. Bier, J.L. Marsh and A.D. Lander (2005) Formation of the BMP activity gradient in the Drosophila embryo. Developmental Cell. 8, 915-924.

71. Kim, Joon, H.-H. Wu, A. D. Lander, K. Lyons, M. M. Matzuk, and A. L. Calof (2005) Gdf11 Controls the Timing of Progenitor Cell Competence in Developing Retina. Science 308, 1927-1930.

72. Xie, F., P.C.-Y. Sheu, A.D. Lander and V. Cristini (2005) Semantic analysis and synthesis of complex biological systems. Intl. J. of Software Engineering and Knowledge Engineering 15, 547-569.

73. Ding, K., M. Lopez-Burks, J. A., S‡nchez-Duran, M. Korc, and A.D. Lander (2005) Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells. J. Cell Biol. 171, 729-38.

74. Lander, A.D., Q. Nie and F.Y.M. Wan (2006) Internalization and End Flux in Morphogen Gradient Formation. J. Computat. Appl. Math.190, 232-251.

75. Lander, A.D., Q. Nie and F.Y.M. Wan (2006) Membrane associated non-receptors and morphogen gradients. Bulletin of Math Biology. 69, 33-54.

76. Lander, A.D. (2007) Morpheus Unbound: Re-imagining the Morphogen Gradient. Cell, 128, 245-256.

77. Zhang, Y.T., A.D. Lander and Q. Nie (2007) Computational analysis of BMP gradients in dorsal-vental patterning of the zebrafish embryo. J. Theor. Biol., 248, 579-589.

78. White, R.J., Q. Nie, A.D. Lander and T.F. Schilling (2007) Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biology, 5, e304.

79. Aikawa, T, C. Whipple, M.E. Lopez, J. Gunn, A. Young, A.D. Lander and M. Korc (2007) Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. J Clin. Invest. 118, 89-99.

80. Whipple C.A., A.D. Lander and M. Korc (2008) Discovery of a novel molecule that regulates tumor growth and metastasis. ScientificWorldJournal 8,1250-1253.

81. Lo, W.-C., C.S. Chou, K.K. Gokoffski, F.Y.M. Wan, A.D. Lander, A.L. Calof and Q. Nie (2009) Feedback regulation in multistage cell lineages. Math Biosci Eng., 6, 59-82.

82. Lander, A.D., K. K. Gokoffski, Frederic Y. M. Wan, Qing Nie and Anne L. Calof (2009) Cell Lineages and the Logic of Proliferative Control. PLoS Biology 7, e15:doi:10.1371/journal.pbio.1000015.

83. Kawauchi, S., J. Kim, R. Santos, H.-H. Wu, A.D. Lander and A.L. Calof (2009) Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development 136, 1453-1464.

84. Beites, C.L., P.L.W. Hollenbeck, J. Kim1, R. Lovell-Badge, A.D. Lander and A.L. Calof 1 (2009) Follistatin modulates a BMP autoregulatory loop to control size and patterning of sensory domains in developing tongue. Development 136, 2187-2197.

85. Lander, A.D., Q. Nie, F.Y.M. Wan, and Y.-T. Zhang (2009) Localized Ectopic Expression of Dpp Receptors in a Drosophila Embryo. Studies in Applied Mathematics, 123, doi: 10.1111/j.1467-9590.2009.00450.x.

86. Lander, A.D., W.-C. Lo, Q. Nie and F.Y.M. Wan (2009) The measure of success: constraints, objectives and tradeoffs in morphogen-mediated patterning. Cold Spring Harbor Perspectives in Biology 1, a002022: doi: 10.1101/cshperspect.a002022.

87. Jen, Y-H, M. Musacchio and A.D. Lander (2009) Glypican-1 controls brain size through regulation of FGF signaling in early neurogenesis. Neural Development 4:33, doi:10.1186/1749-8104-4-33

88. Liu, J., M.B. Dillencourt, L.F. Bic, D. Gillen and A.D. Lander (2009) Distributed Individual-Based Simulation. In: Euro-Par 2009 – Parallel Processing: Proceedings of the 15th International European Conference on Parallel and Distributed Computing, Lecture Notes in Computer Science, vol. 5704. H. Sips, D. Epema and H-X. Lin, Eds. Springer, Heidelberg. pp590-601. doi:10.1007/978-3-642-03869-3_56

89. Kawauchi, S., R. Santos, M.E. Lopez-Burks, C.M. Young, M.P. Hoang, A. Chua, T. Lao, M.S. Lechner, L. Kitzes, B. Hallgrimsson, A.L. Calof and A.D. Lander (2009) Multiple organ system defects and transcriptional dysregulation in a mouse model of Cornelia de Lange Syndrome. PLoS Genetics, 5: e1000650. doi:10.1371/journal.pgen.1000650

90. Lander, A.D. (2009) The ‘stem cell’ concept: is it holding us back? J. Biol. 8, 70. doi:10.1186/jbiol177

91. Gokoffski, K.K., Kawauchi, S., H.-H. Wu, R. Santos, P.W.L. Hollenbeck, A.D. Lander and A.L. Calof (2009) Feedback regulation of neurogenesis in the mammalian olfactory epithelium: New insights from genetics and systems biology. In: Neurobiology of Olfaction, A. Menini, Ed. CRC press. ISBN: 9781420071979

92. Lander, A.D. (2010) The edges of understanding. BMC Biol. 8: 40doi:10.1186/1741-7007-8-40. PMCID: PMC2864098

93. Potkin, S. G., F. Macciardi, M. Vawter, G. Guffanti, Q. Wang, J.A. Turner, A. Lakatos, M.F. Miles, A. Lander, and X. Xie (2010) Identifying Gene Regulatory Networks in Schizophrenia. Neuroimage 53, 839-847. PMCID: PMC3055795

94. Kuo, W.-J., M. Digman and A.D. Lander (2010) Heparan sulfate acts as a BMP co-receptor by facilitating ligand-induced receptor hetero-oligomerization. Mol. Biol. Cell 21, 4028-4041. doi 10.1091/mbc.E10-04-0348. PMCID: PMC2982130

95. Chou, C.S., W.-C. Lo, K. K. Gokoffski, Y.-T. Zhang, F.Y.M. Wan, A. D. Lander, A. L. Calof, and Q. Nie (2010) Spatial dynamics of multi-stage cell lineages in tissue stratification. Biophys. J., 99, 3145-3154. PMCID: PMC2980753

96. Lander, A.D. (2011) Pattern, growth and control. Cell 144, 955-969. PMCID: PMC3128888

97. Chien, R., W. Zeng, S. Kawauchi, M.A. Bender, R. Santos, H.C. Gregson, J.A. Schmiesing, D. Newkirk, X. Kong, A.R. Ball Jr., A.L. Calof, A.D. Lander, M Groudine and K. Yokomori (2011) Cohesin mediates chromatin interactions that regulate mammalian ?-globin expression. J. Biol. Chem., 286, 17870-17878. doi/10.1074/jbc.M110.207365. PMCID: PMC3093862

98. Lander, A.D. (2011) The individuality of stem cells. BMC Biol, 9, 40. doi:10.1186/1741-7007-9-40. PMCID: PMC3110137

99. Lander, A.D., Q. Nie, B. Vargas and F.Y.M. Wan (2011) Size-normalized robustness of Dpp gradient in Drosophila wing imaginal disc. J. Mechanics of Materials and Structures, 6, 321-350. PMCID: PMC3154743

100. Lei, J., F.Y.M. Wan, A.D. Lander and Q. Nie (2011) Robustness of signaling gradient in Drosophila wing imaginal disc. Discrete & Continuous Dynamical Systems Series B, 16(3), 835 – 866. doi:10.3934/dcdsb.2011.16.835 (Winner, 2011 DCDS-B Best Paper Award).

101. Gokoffski, K.K., H.-H. Wu, C.L. Beites, J. Kim, E.J. Kim, M.M. Matzuk, J.E. Johnson, A.D. Lander and A.L. Calof (2011) Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development, 138, 4131-4142. doi:10.1242/dev.065870. PMCID: PMC3171217

102. Nahmad, M and A.D. Lander (2011) Spatiotemporal mechanisms of morphogen gradient interpretation. Curr. Opin. Genet. Devel. 21, 726-31. PMCID: PMC3423890

103. Muto, A., A.L.Calof, A.D. Lander and T.F. Schilling (2011) Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome. PLoS Biology, 9, e1001181. PMCID: PMC3201921

104. Lander A.D., J. Kimble, H. Clevers, E. Fuchs, D. Montarras, M. Buckingham, A.L Calof, A. Trumpp and T. Oskarsson (2012) What does the concept of the stem cell niche really mean today? BMC Biology, 10, 19. PMCID: PMC3298504

105. Zhou, S., W.-C. Lo, J. Suhalim, M. A Digman, E. Gratton, Q. Nie, and A. D. Lander (2012) Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc. Current Biology, 22, 668-675. DOI: 10.1016/j.cub.2012.02.065. PMCID: PMC3338872

106. Kim, M.S., J.-R. Kim, D. Kim, A.D. Lander and K.-H. Cho (2012) Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster BMC Systems Biol. 6, 31 doi:10.1186/1752-0509-6-31. PMCID: PMC3434043

107. Youssefpour, H., X. Li, A.D. Lander, and J. Lowengrub (2012) Multispecies model of cell lineages and feedback control in solid tumors. J. Theor. Biol. 304:39-59. PMID: 22554945. PMCID: PMC3436435

108. Cai, A.Q., K. Radtke, A. Linville, A.D. Lander, Q. Nie, T.F. Schilling (2012) Cellular retinoic acid binding proteins (Crabps) are essential for hindbrain patterning and signal robustness in zebrafish. Development 139, 2150-2155. doi:10.1242/dev.077065. PMCID: PMC3357909

109. Zhang, L., A.D. Lander and Q. Nie (2012) A reaction-diffusion mechanism influences cell lineage progression as a basis for formation, regeneration, and stability of intestinal crypts. BMC Systems Biology 6, 93. doi:10.1186/1752-0509-6-93. PMCID: PMC3434027

110. Palmer, R., J. McGeary, S. Francazio, A. Heath., A.D. Lander, B. Raphael, V. Knopik. (2012) The Genetics of Alcohol Dependence: Advancing Towards Systems-based Approaches. Drug and Alcohol Dependence, 125: 179-191. dx.doi.org/10.1016/j.drugalcdep.2012.07.005, PMID:22854292. PMCID: PMC3470479

111. Schilling T.F., Q. Nie and A.D. Lander (2012) Dynamics and precision in retinoic acid morphogen gradients. Curr Opin Genet Dev. 22:562-569. doi:pii: S0959-437X(12)00142-6. 10.1016/j.gde.2012.11.012. PMID: 23266215. NIHMS430584.

112. Lander, A.D. (2013) How Cells Know Where They Are. Science. 339, 923-927. PMID: 23430648

113. S. Remeseiro, A. Cuadrado, S. Kawauchi, A.L. Calof, A.D. Lander and A. Losada (2013) Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome. Biochim Biophys Acta 1832, 2097-102. doi: 10.1016/j.bbadis.2013.07.020. PMCID: PMC3825806

114. Visnes, T., F. Giordano, A. Kuznetsova, JA Suja, A.D. Lander, A.L. Calof and L. Stršm (2013) Localization of the SMC-loading complex Nipbl/Mau2 during mammalian meiotic prophase I. Chromosoma, 123, 239-252. PMID: 24287868; PMCID: PMC4031387.

115. Konstorum, A., S.A. Sprowl, A.D. Lander, M.L. Waterman, and J.S. Lowengrub (2014) Elaboration of a multispecies model of solid tumor growth with tumor-host interactions. Proceedings of the 3rd International Conference on Theory and Application in Nonlinear Dynamics (ICAND 2012), In: Understanding Complex Systems Vol XI, V. In, A. Palacios, and P. Longhini, Eds. Springer Verlag., p. 295-304. ISBN 978-3-319-02924-5.

116. Konstorum A., S.A. Sprowl, M.L. Waterman, A.D. Lander, and J. Lowengrub (2014) Predicting mechanism of biphasic growth factor action on tumor growth using a multi-species model with feedback control. J. Coupled Systems and Multiscale Dynamics, 1, 459-467.

117. Srinivasan, S., J.S. Hu, D.S. Currle, E.S. Fung, W.B. Hayes, A.D. Lander and E.S. Monuki (2014) A BMP-FGF Morphogen Toggle Switch Drives the Ultrasensitive Expression of Multiple Genes in the Developing Forebrain. PLoS Computational Biol 10, e1003463. doi:10.1371/journal.pcbi.1003463. PMID: 24550718, PMCID: PMC3923663.

118. McHale, P. and A.D. Lander (2014) The Protective Role of Symmetric Stem Cell Division on the Accumulation of Heritable Damage. PLoS Computational Biology Aug 14;10(8):e1003802. doi: 10.1371/journal.pcbi.1003802. PMID: 25121484, PMCID: PMC4133021

119. Lander A.D. (2014) Making sense in biology: An appreciation of Julian Lewis. BMC Biology 12, 57. doi:10.1186/s12915-014-0057-5

120. Muto, A., S. Ikeda, M.E. Lopez-Burks, Y Kikuchi, A.L. Calof, A.D. Lander and T.F. Schilling (2014) Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development. PLoS Genetics, 10(9):e1004671. doi: 10.1371/journal.pgen.1004671.

121. Lo, W-C, S. Zhou, F.Y.M. Wan, A.D. Lander and Q. Nie (2015) Robust and Precise Morphogen-mediated Patterning: Tradeoffs, Constraints, and Mechanisms. J. Royal Soc. Interface. 12, 20141041. DOI: 10.1098/rsif.2014.1041.

122. Buzi, G., Lander, A.D., and Khammash, M. (2015). Cell lineage branching as a strategy for proliferative control. BMC Biology, 13, 13. doi:10.1186/s12915-015-0122-8.

123. Chen C.C., Wang L., Murray P.J., Jiang T.X., Plkus M.V., Lee O., Shi S., Widelitz R.B., Lander A.D. and Chuong C.M. (2015) Organ-level quorum sensing directs regeneration in hair stem cell populations. Cell 161, 277-290. dos: 10.1016/j.cell.2015.02.016.

124. Kunche, S., H. Yan, A.L. Calof, J.S. Lowengrub and A.D. Lander (2016) Feedback, lineages and self-organized morphogenesis. PLoS Computational Biol, 12, e1004814. doi:10.1371/journal.pcbi.1004814.

125. Wilkins, J.F., P.T. McHale, J. Gervin and A.D. Lander (2016) Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis. PLoS Genetics 12(4): e1006003. doi:10.1371/journal.pgen.1006003

126. Lopez-Burks, M.E., R. Santos, S. Kawauchi, A.L. Calof and A.D. Lander (2016) Genetic enhancement of limb defects in a mouse model of Cornelia de Lange Syndrome. Am J Med Genet C Semin Med Genet. 2016 Jun;172(2):146-54. doi: 10.1002/ajmg.c.31491.

127. Kawauchi, S., R. Santos, A. Muto, M.E. Lopez-Burks, T.F. Schilling, A.D. Lander and A.L. Calof (2016) Using Mouse and Zebrafish Models to Understand the Etiology of Developmental Defects in Cornelia de Lange Syndrome. Am J Med Genet C Semin Med Genet. 2016 Jun;172(2):138-45. doi: 10.1002/ajmg.c.31484. PMID: 27120001.

128. Santos R., S. Kawauchi, R.E. Jacobs, M.E. Lopez-Burks, H. Choi, J. Wikenheiser, B. Hallgrimsson, H.A. Jamniczky, S.E. Fraser, A.D. Lander, and A.L. Calof (201X) Conditional creation and rescue of Nipbl-deficiency in mice reveals multiple determinants of risk for congenital heart defects.  PLOS Biology, 14, e2000197. doi: 10.1371/journal.pbio.2000197.  PMID: 27606604.

129.  Hsia, K., M.-J. Yang, W.-M. Chen, C.-L. Yao, C.-H. Lin, C.-C. Loong, Y.-L. Huang, Y.-T. Lin, A.D. Lander, H. Lee and J.H. Lu (2017). Sphingosine-1-Phosphate Improves Endothelialization with Reduction of Thrombosis in Recellularized Human Umbilical Vein Graft by Inhibiting Syndecan-1 Shedding. Acta Biomaterialia, Mar 15;51:341-350. doi: 10.1016/j.actbio.2017.01.050. Epub 2017 Jan 18. PubMed PMID: 28110073

130. Wortman J.C., M. Nahmad, P.C. Zhang, A.D. Lander and C.C. Yu (2017) Expanding signaling-molecule wavefront model of uniform growth and cell polarization in the Drosophila wing primordium. PLoS Computational Biol, 13, e1005610. doi: 10.1371/journal.pcbi.1005610. PMID: 28671940.

Newkirk, D., Y.-Y. Chen, R. Chien, W. Zeng, J. Biesinger, E. Flowers, S. Kawauchi, R. Santos, A. Calof, A. Lander, X. Xie, K. Yokomori (2017) The Effect Of Nipped-B-Like (Nipbl) Haploinsufficiency On Genome-Wide Cohesin Binding And Target Gene Expression: Modeling Cornelia de Lange Syndrome. bioRxiv 134825; doi: https://doi.org/10.1101/134825.